Principal Investigator


Professor, Department of Medical Biophysics, University of Toronto
Cross-appointed to Institute of Biomaterials and Biomedical Engineering
Cross-appointed to Leslie Dan Faculty of Pharmacy
Cross-appointed to Institute of Medical Science
Associate Research Director of Princess Margaret Cancer Centre


Read Dr. Zheng’s recent interview with Future Medicine
Dr. Zheng received his PhD in 1999 from SUNY Buffalo in Medicinal Chemistry. Following two years of postdoctoral training in photodynamic therapy at the Roswell Park Cancer Institute, he joined the University of Pennsylvania in 2001 as an Assistant Professor of Radiology, where he established the molecular imaging chemistry program and introduced photodynamic molecular beacons and lipoprotein-like nanoparticles. Since moving to Canada in 2006, his research has been focused on developing clinically translatable technology platforms to combat cancer. His lab discovered porphysome nanotechnology (Nature Materials 2011), which was named one of the “top 10 cancer breakthroughs of 2011” by the Canadian Cancer Society. His lab also discovered that on exposure to low-frequency ultrasound, porphyrin microbubbles form nanoparticles that possess the same optical and therapeutic properties as the original microbubble, and can be used simultaneously for imaging and drug delivery (Nature Nano 2015). Dr. Zheng is an Associate Editor for Bioconjugate Chemistry and a Fellow of the American Institute for Medical and Biological Engineering. In 2019, he was awarded a Tier 1 Canada Research Chair in Cancer Nanomedicine.

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