Lovell JF, Jin H, Ng KK & Zheng G
Angewandte Chemie International Edition, 2010
Out in the open: Hydrophobically modified molecular beacons were inserted into lipid nanoparticles. Upon addition of the target DNA to a solution of the lipid nanoparticles, irreversible nanoparticle aggregation occurred (see picture). This aggregation phenomenon results from the opening of the molecular beacons.