Zhang Z, Li H, Liu Q, Zhou L, Zhang M, Luo Q, Glickson J, Chance B & Zheng G Biosensors and Bioelectronics, 2004 One of the biochemical “hallmarks” of malignancy is enhanced tumor glycolysis, which is primary due to the overexpression of glucose transporters (GLUTs) and the increased activity ofContinue Reading
Chen J, Stefflova K, Niedre MJ, Wilson BC, Chance B, Glickson JD & Zheng G Journal of the American Chemical Society, 2004 We report a new concept for type-II photosensitization, based on incorporating the photosensitizer (PS) and a singlet-oxygen (1O2) quenching/scavenging molecule onto a disease-targeting linker, such that the PSContinue Reading
Zhang Z, Blessington D, Li H, Busch TM, Glickson J, Luo Q, Chance B & Zheng G Journal of Biomedical Optics, 2004 The effect of photodynamic therapy (PDT) treatment on the metabolic state of tumor mitochondria is investigated by imaging of tumor redox status. PDT is performed using the photosensitizerContinue Reading
Li H, Zhang Z, Blessington D, Nelson DS, Zhou R, Lund-Katz S, Chance B, Glickson JD & Zheng G Academic Radiology, 2004 Rationale and objectives: The purpose of this study was to define and characterize carbocyanine labeled low-density lipoprotein (LDL) to be used in the optical imaging of LDL receptorContinue Reading
