Efficient systemic delivery of siRNA by using high-density lipoprotein-mimicking peptide lipid nanoparticles
Lin Q, Chen J, Jin H, Ng KK, Yang M, Cao W, Ding L, Zhang Z & Zheng G Nanomedicine, 2012 The main challenge for RNAi therapeutics lies in systemic delivery of siRNA to the correct tissues and transporting them into the cytoplasm of targeted cells, at safe, therapeutic levels.Continue Reading