Pellow C, Tan J, Chérin E, Demore CME, Zheng G, Goertz DE Ultrasonics, 2020 DOI: 10.1016/j.ultras.2020.106245 Emerging contrast imaging studies have highlighted the potential of nanobubbles for both intravascular and extravascular applications. Reports to date on nanobubbles have generally utilized low frequencies (<12 MHz), high concentrations (>109 mL−1), and B-mode or contrast-modeContinue Reading

Pellow C, O’Reilly MA, Hynynen K, Zheng G & Goertz DENano Letters, 2020DOI:10.1021/acs.nanolett.0c01310 Ultrasound-activated nanobubbles are being widely investigated as contrast agents and therapeutic vehicles. Nanobubbles hold potential for accessing the tumor extravascular compartment, though this relies on clinically debated passive accumulation for which evidence to date is indirect. WeContinue Reading

Pellow C, Acconcia CN, Zheng G & Goertz DE Physics in Medicine and Biology, 2018 DOI: 10.1088/1361-6560/aae571 Nanobubbles hold potential for expanding utility of ultrasound contrast-based applications to extravascular targets, but their acoustic response and the effects of the surrounding environment remain relatively unexplored. Here we investigate the dynamics ofContinue Reading