Lou J, Aragaki M, Bernards N, Chee T, Gregor A, Hiraishi Y, Ishiwata T, Leung C, Ding L, Kitazawa S, Koga T, Sata Y, Ogawa H, Chen J, Kato T, Yasufuku K, Zheng G Biomaterials DOI: 10.1016/j.biomaterials.2022.121918 In combination with immune checkpoint inhibitors, photodynamic therapy can induce robust immune responsesContinue Reading

Cressey P, Abuillan W, Ibrahim N, Alhoussein J, Konovalov O, Zheng G, Makky A ChemPhysChem DOI: 10.1002/cphc.202200687 Lipid-porphyrin conjugates are versatile compounds which can self-assemble into liposome-like structures with multifunctional properties. Most of the conjugates that have been described so far, consisted in grafting pyropheophorbide-a (Pyro-a) or other porphyrin derivativesContinue Reading

Margalik DA, Chen J, Ho T, Ding L, Dhaliwal A, Doria AS, Zheng G Bioconjugate Chemistry DOI: 10.1021/acs.bioconjchem.2c00445 Porphysomes (PS) were explored to incorporate different types of diethylenetriaminepentaacetic-acid-gadolinium-(III) (Gd-DTPA)-lipids into their bilayer membrane to assess PS potential as an MRI contrast agent. The Gd-dPS-BSA by integration of over 30% Gd-DTPA-bis(stearylamide)Continue Reading