Lovell JF, Chan MW, Qi Q, Chen J & Zheng G Journal of the American Chemical Society, 2011 Photodynamic therapy (PDT) stands to benefit from improved approaches to real-time treatment monitoring. One method is to use activatable photosensitizers that can both induce cell death (via singlet oxygen) and monitor itContinue Reading

Jin CS & Zheng G Lasers in Surgery and Medicine, 2011 Background and Objective: In photodynamic therapy (PDT), photosensitizers are activated by light of a specific wavelength and produce cytotoxic molecules to damage diseased tissues. Most photosensitizers are hydrophobic and easily aggregate in aqueous solution. To maintain their photodynamic activityContinue Reading

Ng KK, Lovell JF & Zheng G Accounts of Chemical Research, 2011 Over hundreds of millions of years, animals have evolved endogenous lipoprotein nanoparticles for shuttling hydrophobic molecules to different parts of the body. In the last 70 years, scientists have developed an understanding of lipoprotein function, often in relationshipContinue Reading