Jin H, Lovell JF, Chen J, Ng KK, Ding L, Zhang Z & Zheng G Photochemical and Photobiological Sciences, 2011 Following cellular delivery, most drugs must escape endosomes and lysosomes and reach the cytosol to be effective. This is particularly significant for nanoparticles, which can carry a large drug payload,Continue Reading
Yang M, Jin H, Chen J, Ding L, Ng KK, Lin Q, Lovell JF, Zhang Z & Zheng G Small, 2011 High-density lipoprotein (HDL)-mimicking peptide–phospholipid scaffold (HPPS) nanoparticles are used as a flexible and biocompatible nanocarrier for the delivery of small interfering RNA (siRNA). The direct cytosolic delivery ability ofContinue Reading
Shi J, Liu TW, Chen J, Green D, Jaffray D, Wilson BC, Wang F & Zheng G Theranostics, 2011 Porphyrin based photosensitizers are useful agents for photodynamic therapy (PDT) and fluorescence imaging of cancer. Porphyrins are also excellent metal chelators forming highly stable metallo-complexes making them efficient delivery vehicles forContinue Reading
Liu TW, Chen J, Burgess L, Cao W, Shi J, Wilson BC & Zheng G Theranostics, 2011 The complimentary ability of different noninvasive imaging technologies with therapeutic modalities can be used in tandem providing high-resolution and highly sensitive imaging of events at the molecular and cellular level providing a meansContinue Reading
