Farhadi A, Roxin Á, Wilson BC, Zheng G Theranostics, 2015 DOI: 10.7150/thno.10694 To impart effective cellular damage via photodynamic therapy (PDT), it is vital to deliver the appropriate light dose and photosensitizer concentration, and to monitor the PDT dose delivered at the site of interest. In vivo monitoring of photosensitizers has inContinue Reading

Huang H, Cruz W, Chen J, Zheng G Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 2015 DOI: 10.1002/wnan.1308 Synthetic lipoproteins represent a relevant tool for targeted delivery of biological/chemical agents (chemotherapeutics, siRNAs, photosensitizers, and imaging contrast agents) into various cell types. These nanoparticles offer a number of advantages for drugs deliveryContinue Reading

Muhanna N, MacDonald TD, Chan H, Jin CS, Burgess L, Cui L, Chen J, Irish JC & Zheng G Advanced Healthcare Materials, 2015 DOI: 10.1002/ange.201803535 64Cu-porphysome nanoparticles enable superior delineation of neoplastic tissues, metastatic lymph nodes, and vascular drainage on head and neck cancer orthotopic rabbit model using positron emissionContinue Reading

Charron DM, Chen J & Zheng G Nanotechnology-Based Precision Tools for the Detection and Treatment of Cancer, 2015 Disease heterogeneity within and between patients necessitates a patient-focused approach to cancer treatment. This exigency forms the basis for the medical practice termed personalized medicine. An emerging, important component of personalized medicineContinue Reading