Lou J, Aragaki M, Bernards N, Chee T, Gregor A, Hiraishi Y, Ishiwata T, Leung C, Ding L, Kitazawa S, Koga T, Sata Y, Ogawa H, Chen J, Kato T, Yasufuku K, Zheng G Biomaterials DOI: 10.1016/j.biomaterials.2022.121918 In combination with immune checkpoint inhibitors, photodynamic therapy can induce robust immune responsesContinue Reading

Cruz W, Huang H, Barber B, Pasini E, Ding L, Zheng G, Chen J, Bhat M Hepatology Communications, 2020 DOI: 10.1002/hep4.1493 Patients with advanced hepatocellular carcinoma (HCC) are often unable to tolerate chemotherapy due to liver dysfunction in the setting of cirrhosis. We investigate high‐density lipoprotein (HDL)‐mimicking peptide phospholipid scaffoldContinue Reading

Harmatys K, Chen J, Charron DM, MacLaughlin CM & Zheng G Angewandte Chemie, 2018 DOI: 10.1002/ange.201803535 Biomimetics are reconstructions of natural systems in engineered forms to exploit their structural or functional properties. Current biomimetics for medical applications use a single biomimetic approach to imitate natural structures, which can be insufficientContinue Reading

Charron DM, Chen J & Zheng G ChemNanoMat, 2016 Nanocarriers incorporating therapeutic and imaging agents within a single nanostructure are emerging tools for drug development and treatment planning. Additional information can be provided using activatable fluorescence that dynamically reports nanocarrier disruption and drug release. Dual-wavelength activation encodes a unique fluorescenceContinue Reading